In-Vitro Cell Stimulation
In-vitro cell stimulation is utilized to research the physiological events in cortex cells on neuro-chip-systems. Findings in the field of in-vitro cell stimulation help improve current applications in neurodiagnostics and -rehabilitation.
The main advantage of neuro-chip-systems is that, due to their inter-neuronal connections, they represent nerve tissue much more comprehensively than single nerve fibers or preparations. These systems also highly suited towards analyzing defined chemical impacts on nerve cells (e.g. neuro-toxic impacts). Reproducible measurements can be conducted over extended periods of time while excluding many interference factors.
Major considerations and solutions:
Ability to modulate the stimulus activity of neurons:
Exact stimulation dosage and reproducibility.
Definition of the geometric field parameters for the induced magnetic field:
Selection of different coil forms and types.
Research different pulse forms:
Optimizing stimulus time and sequence (with or without switching the polarity).
Improved stimulus effect for induced stimulation:
Application of different pulse forms and patterns.