Real Time EEG Triggered TMS

A hot topic in today’s brain research is state-depending modulation of brain networks in real time by applying personalized TMS patterns. This real-time application allows you to investigate cortical excitability and induction of long lasting plasticity in network pathways with respect to the „right“ timing with the „right“ TMS stimuli.

Synchronizing the timing of the individual stimulation patters with the actual state parameters is technically challenging. For following the dynamics in different brain states an online streaming EEG data acquisition equipment and a real-time capable TMS device is essential.

Major considerations and solutions:

Safe operation of the stimulator
Safety channel to immediately stop of the stimulation if necessary.
Patented safety concept for setting safety borders of stimulation intensity and frequency.

Combination of QPS stimulation with EEG
Biphasic QPS pulses for minimization of stimulation artifact.
Advanced shielding of stimulator and to avoid interferences by mains noise.

Comparison of various stimulation protocols
All-in-one stimulation equipment enables QPS, TBS and rTMS in one device.

Integration into existing research labs
Various possibilities to control the stimulation with existing equipment.

Why MAG & More:
Full external controllability
Full external controllability
Various coils
Various coils
Precise timing
Precise timing
Electrical shielding
Electrical shielding
Integrated navigation points
Integrated navigation points
Reproducability
Reproducability
Half- and full wave
Half- and full wave
High speed stimulation
High speed stimulation